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anastrozole arimidex

CAS 120511-73-1Pharmaceutical Raw Materials Anastrozole Arimidex Steorids Powder

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CAS 120511-73-1Pharmaceutical Raw Materials Anastrozole Arimidex Steorids Powder 

Description:
Anastrozole
Alias: Arimidex
CAS No: 120511-73-1
MF: C17H19N5
MW: 293.37
Melting Point: 81.0~84.0°C
Anastrozole / Arimidex Medicine Injectable Anabolic Steroid Hormones Without Side Effects
Purity: 99%
Appearance:  White Crystalline Powder


How effective is anastrozole in preventing breast cancer?

1920 women were randomly assigned to 5 years anastrozole and 1944 to placebo. After a median follow-up of 131 months (IQR 105-156), a 49% reduction in breast cancer was observed for anastrozole (85 vs 165 cases, hazard ratio [HR] 0·51, 95% CI 0·39-0·66, p<0·0001).


Does anastrozole weaken your immune system?

Does hormone therapy affect the immune system? Taking hormone therapy, including tamoxifen, letrozole, anastrozole, exemestane and goserelin, does not affect your immune system.


Is 5 years on anastrozole enough?

"After 5 years of standard endocrine therapy, 2 additional years of anastrozole are sufficient," said Michael Gnant, director and chairperson of the department of surgery at the Comprehensive Cancer Center at the Medical University of Vienna, who presented the research.


Is it better to take anastrozole in the morning or at night?

If hot flashes are troublesome: • Take your anastrozole at bedtime. hot flashes continue to bother you. There may be medications available. Muscle or joint pain may occur a few days after your treatment


COA


Items Standard Results
Description White crystalline powder Complies
Identification IR Conform with standard IR
HPLC Conform with standard HPLC
Reactive Conform
Solubility Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile Complies
Total Impurity max.0.5% 0.18%
Total Unspecified Impurity max. 0.2% 0.08%
Individual unspecified impurlty max. 0.1% 0.05%
Related compound B max. 0.2% 0.07%
Related compound C max. 0.2% 0.04%
Related compound D max. 0.1% 0.05%
Related compound E max. 0.1% 0.06%
Limit of cyclohexane max. 0.08% ND
Limit of ethylacetate max. 0.1% 0.07%
Melting point 81.0~84.0℃ 82.5~83.2℃
Water max. 0.3% 0.21%
Residue on ignition max. 0.1% 0.07%
Heavy Metals max.0.001% Complies
Assay(HPLC) 98.0%~102.0% 99.80%
Storage Cool and dry
Conclusion It complies to USP32 .


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